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In recent months, Pakistan has been slipping deeper into crisis: emergency rule, the assassination of Benazir Bhutto and militancy has started to creep in from the tribal areas into the heart of the country.
Pakistan is not just any state - its strategic importance causes deep anxiety around the world, especially in Washington, given the country's nuclear capability.
But how are the weapons protected and what can be done to stop them getting into the wrong hands?
Gorden Corera, the BBC's security correspondent, looks at whether the world should be worried about the safety of Pakistan's nuclear weapons.
Is it a case of media hype and fearmongering or is it a real threat to Pakistan and the world's security?
It is a story that describes the tense and difficult relationship between the US and Pakistan.
